Research Publications

Our science is regularly recognized in top peer-reviewed scientific journals.

Contributing to the scientific community

We apply the highest scientific rigor to our work and share learnings to advance science that can benefit society. As a result, our research is frequently published in peer-reviewed journals. Review a selection of our most recent publications.

Recent publication highlights

*AbbVie Post-Doc at time of work

Result(s) found

Synthetic lethality of mRNA quality control complexes in cancer Nature | DOI:10.1038/s41586-024-08398-6
AbbVie authors: Vivian Prindle, Adam E Richardson, Kimberly Rose Sher, Sarah Kongpachith, Kaitlin Mary Kentala, Sakina M Petiwala, Dong Cheng, Deborah L Widomski, Phuong N Le, Maricel Torrent, Anlu Chen, Stephen G Walker, Marianne Barbara Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, Fritz G Buchanan, Daniel Verduzco, Brian R Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik
In-Cell Approach to Evaluate E3 Ligases for Use in Targeted Protein Degradation Journal of the American Chemical Society | DOI: 10.1021/jacs.5c02741
AbbVie authors: Yunan Zheng, Zeqi Niu*, Violeta Marin, Jonathon Young, Kedar Puvar, Scott E. Warder, Anil Vasudevan, Justin M. Reitsma
Explainable Machine Learning for ETR and Drug Chameleonicity Journal of Medicinal Chemistry | DOI: 10.1021/acs.jmedchem.5c00536
AbbVie authors: Edward Price, Matthieu Dagommer, Mattson Thieme, Richard Hong, J. Cory Kalvass, Stella Doktor, Alexey Rivkin, Yue-Ting Wang, Philip Cox, Abhishek Pandey, David DeGoey
Role of hydrogen bonding and water clusters in deamidation of peptide in glycerol-water solutions International Journal of Pharmaceutics | DOI: 10.1016/j.ijpharm.2025.125420
AbbVie authors: Tapiwa Chiura*, Dana Filoti, Markus Hollman, Shaoxin Feng, Evgenyi Shalaev
AURA: Accelerating drug discovery with accuracy, utility, and rank-order assessment for data-driven decision making Journal of Pharmaceutical Sciences | DOI: 10.1016/j.xphs.2024.12.006
AbbVie authors: Edward Price, Virginia Saulnier, John Cory Kalvass, Stella Doktor, Manuel Weinheimer, Majdi Hassan, Spencer Scholz, Marjoleen Nijsen, Gary Jenkin
Novel Integration of Spatial and Single-Cell Omics Data Sets Enables Deeper Insights into IPF Pathogenesis Proteomes | DOI: 10.3390/proteomes13010003
AbbVie Authors: Fei Wang*, Liang Jin, Xue Wang, Baoliang Cui, Yingli Yang, Lori Duggan, Annette Schwartz Sterman, Sarah M. Lloyd*, Lisa A. Hazelwood, Neha Chaudhary, Bhupinder Bawa, Lucy A. Phillips, Yupeng He, Yu Tian
Combinability of epcoritamab CD20-targeting T-cell engager and CD20 antibody-targeted therapies in B-cell non-Hodgkin lymphoma Leukemia & Lymphoma | DOI: 10.1080/10428194.2025.2504719
AbbVie authors: Durga B. Dandamudi, Iwona M. Konieczna, Kelly M. Calabrese, Ramesh Iyer, Paul Ellis, Luis Rodriguez, Apurvasena Parikh, Cormac Cosgrove, Adam S. Chervin, Edward B. Reilly, Pearlie Epling-Burnette, Edith Szafer-Glusman
Toxicologic Pathology Forum: Opinion on New Technologies and Trends Disrupting Drug Discovery and Development: How Can the Next Generation of Toxicologic Pathologists Be Prepared for Evolving Roles? Toxicologic Pathology | DOI: 10.1177/01926233251321805
AbbVie authors: Rebecca Kohnken, Lauren Himmel, Magali Guffroy, Eric A.G. Blomme
Using Human iPSC-Derived Astrocytes to Investigate Transcription Factor-Driven Astrocyte to Neuron Transdifferentiation Methods in molecular biology | DOI: 10.1007/978-1-0716-4530-7_2
AbbVie authors: Ruven Wilkens, Juergen Korffmann, Nathalie Andrea Nicolaisen, Milan Modic, Julian Roewe, Carina Habich, Lamiaa Bahnassawy, Miroslav Cik, Peter Reinhardt
Automated High-Throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition Journal of Proteome Research | DOI: 10.1021/acs.jproteome.4c00696
AbbVie authors: Hui Jing, Gregory K. Potts, Sameera Senaweera, Violeta L. Marin, Adam Banlasan, Hua Tang, James E. Kath, Shitalben Patel, Maricel Torrent, Renze Ma, Jon D. Williams
Nonclinical teratogenicity safety assessment of CRBN-engaging targeted protein degraders: Points to consider Regulatory Toxicology and Pharmacology | DOI: 10.1016/j.yrtph.2025.105793
AbbVie authors: Lise Loberg
Fluorogenic Platform for Real-Time Imaging of Subcellular Payload Release in Antibody–Drug Conjugates Journal of Pharmaceutical Sciences | DOI: 10.1021/jacs.4c16842
AbbVie Authors: Paulin L. Salomon, Kathy A. Sarris, Zhi Wang, Rachel D. Wills *, Violeta L. Marin, Michael J. McPherson
Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis Nature Genetics | DOI: 10.1038/s41467-025-58310-7
AbbVie authors: Meri Oliva, Chen-Lin Hsieh, Fanying Tang, Kathleen M. Smith, Bridget Riley-Gillis
Establishing endotoxin limits to enhance the reliability of in vitro immunogenicity risk assessments mAbs | DOI: 10.1080/19420862.2025.2458627
AbbVie authors: Yun Hee Jeong, Gillian Lennon, Geertruida Veldman, Daniel M. Serna, Alexander Ibrahimov
A novel in vitro serum stability assay for antibody therapeutics incorporating internal standards mAbs | DOI: 10.1080/19420862.2025.2479529
AbbVie authors: Yihan Li, Vikram Shenoy, Heidi Mae Jackson, Yuting Wang, Karen Eileen Parrish, Gary James Jenkins, Hetal Sarvaiya
Machine learning–enhanced screening funnel for clinical trials in Alzheimer's disease Alzheimer's and Dementia: Translational Research and Clinical Interventions | DOI: 10.1002/trc2.70084
AbbVie authors: Scott Gladstein, Liuqing Yang, Dustin Wade Wooten, Xin Huang, Robert Alan Comley, Qi Guo
Treatment journey clustering with a novel kernel k-means machine learning algorithm: a retrospective analysis of insurance claims in bipolar I disorder Brain Informatics | DOI: 10.1186/s40708-025-00258-x
AbbVie authors: Matthew David Littman, Huy-Binh Nguyen, Joanna H Campbell
Application of drug-induced growth rate inhibition and intracellular drug exposures for comprehensive evaluation of cellular drug sensitivity Scientific Reports | DOI: 10.1038/s41598-025-86919-7
AbbVie authors: Dolonchampa Maji, Malerie Wolke, Shamim Khaja, John Paul Savaryn, John C Kalvass, Gary James Jenkins
Freezing-induced protein aggregation in a bispecific antibody: Characterization and mechanistic insights Journal of Pharmaceutical Sciences | DOI: 10.1016/j.xphs.2025.103711
AbbVie authors: Xiaofeng Lu, Blanca Domingo-Yenes, Noah Cohen, Elissa Grzincic
Stopped clinical trials give evidence for the value of genetics Nature Genetics | DOI: 10.1038/s41588-024-01834-3
AbbVie authors: Emily King

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